Changing DNS on IPv4 vs IPv6

I want to change my default DNS to Google DNS.

Many sites like streamble.com are blocked in my default service provider DNS. After some research I found that, if we switch to Google DNS, we can access those sites.

But we have two protocol versions, IPv4 and IPv6.

So which one is preferred to change the DNS, or whats the difference between these two when comes to changing DNS.